1660s, "first, earliest, existing from the beginning," especially in reference to inhabitants of lands colonized by Europeans, from aborigines (see aborigine) + -al (1). The specific Australian sense is attested from 1820. The noun meaning "an original inhabitant, an autochthon" is attested from 1760. Related: Aboriginally; aboriginality (1848); aboriginalism (1859).
Definition
Pertaining to election or electors.
Etymology
1670s, "pertaining to electors," in reference to Germany, from elector + -al (1). In general sense from 1790. Related: Electorally. The U.S. electoral college so called from 1808 (the term was used earlier in reference to Germany).
Etymology - 1911, from German Gen, coined 1905 by Danish scientist Wilhelm Ludvig Johannsen (1857-1927), from Greek genea "generation, race" (from PIE root *gene- "give birth, beget"). De Vries had earlier called them pangenes. Gene pool is attested from 1946.
Acording to the FDA 9/20/2022 11:22pm CST - Human gene therapy seeks to modify or manipulate the expression of a gene or to alter the biological properties of living cells for therapeutic use 1.
Gene therapy is a technique that modifies a person’s genes to treat or cure disease. Gene therapies can work by several mechanisms:
Gene therapy products are being studied to treat diseases including cancer, genetic diseases, and infectious diseases.
There are a variety of types of gene therapy products, including:
Gene therapy products are biological products regulated by the FDA’s Center for Biologics Evaluation and Research (CBER). Clinical studies in humans require the submission of an investigational new drug application (IND) prior to initiating clinical studies in the United States. Marketing a gene therapy product requires submission and approval of a biologics license application (BLA).
Accoding to webster : the insertion of usually genetically altered genes into cells especially to replace defective genes in the treatment of genetic disorders or to provide a specialized disease-fighting function
Medical Definition of gene therapy : the insertion of usually genetically altered genes into cells especially to replace defective genes in the treatment of genetic disorders or to provide a specialized disease-fighting function (as the destruction of tumor cells)
No Etymology of this word
1828 Webters Dict1onary:
Etymology:
1530s, "state or condition of being smaller," a sense now obsolete, from French minorité (15c.), or directly from Medieval Latin minoritatem (nominative minoritas), from Latin minor "less, lesser, smaller, junior" (see minor (adj.)).
Meaning "state of being under legal age" is from 1540s; that of "smaller number or part, smaller of two aggregates into which a whole is divided numerically" is from 1736. Specifically as "the smaller division of any whole number of persons" (in politics, etc.) is by 1789. The meaning "group of people separated from the rest of a community by race, religion, language, etc." is from 1919, originally in an Eastern European context.
Definition of vaccine
1 : a preparation that is administered (as by injection) to stimulate the body's immune response against a specific infectious agent or disease: such as
a : an antigenic preparation of a typically inactivated or attenuated (see ATTENUATED sense 2) pathogenic agent (such as a bacterium or virus) or one of its components or products (such as a protein or toxin)
a trivalent influenza vaccine
oral polio vaccine
Many vaccines are made from the virus itself, either weakened or killed, which will induce antibodies to bind and kill a live virus. Measles vaccines are just that, weakened (or attenuated) measles viruses.
— Ann Finkbeiner et al.
… a tetanus toxoid-containing vaccine might be recommended for wound management in a pregnant woman if [greater than or equal to] 5 years have elapsed … .
— Mark Sawyer et al.
In addition the subunit used in a vaccine must be carefully chosen, because not all components of a pathogen represent beneficial immunological targets.
— Thomas J. Matthews and Dani P. Bolognesi
b
: a preparation of genetic material (such as a strand of synthesized messenger RNA) that is used by the cells of the body to produce an antigenic substance (such as a fragment of virus spike protein)
… Moderna's coronavirus vaccine … works by injecting a small piece of mRNA from the coronavirus that codes for the virus' spike protein. … mRNA vaccine spurs the body to produce the spike protein internally. That, in turn, triggers an immune response.
— Susie Neilson et al.
The revolutionary messenger RNA vaccines that are now available have been over a decade in development. … Messenger RNA enters the cell cytoplasm and produces protein from the spike of the Covid-19 virus.
— Thomas F. Cozza
Viral vector vaccines, another recent type of vaccine, are similar to DNA and RNA vaccines, but the virus's genetic information is housed in an attenuated virus (unrelated to the disease-causing virus) that helps to promote host cell fusion and entry.
— Priya Kaur
NOTE: Vaccines may contain adjuvants (such as aluminum hydroxide) designed to enhance the strength and duration of the body's immune response.
2 : a preparation or immunotherapy that is used to stimulate the body's immune response against noninfectious substances, agents, or diseases
The U.S. Army is also testing a ricin vaccine and has reported success in mice.
— Sue Goetinck Ambrose
… many of the most promising new cancer vaccines use dendritic cells to train the immune system to recognize tumor cells.
— Patrick Barr
"matter used in vaccination," 1846, from French vaccin, noun use of adjective, from Latin vaccina, fem. of vaccinus "pertaining to a cow" (see vaccination). Related: Vaccinal; vaccin